Prevalence of Sickle Cell Anemia and Thalassemia among Anemic Patients of Al-Noor Specialist Hospital, Makkah, KSA

نویسندگان

  • H. Faidah
  • M. Samy
  • A. A Tashkandi
چکیده

This study aimed to to determine the prevalence of Sickle cell diseases and trait and high hemoglobin (Hb) A2 βthalassemia in the province of Makkah among patients of Al-Noor Specialist hospital, Makkah. Retrospective studying the results of 620 requested saudi patients (256 male and 364 female) suffer from Anemia for gel electrophoresis. Covering the period between 1 January 2012 to 30 December 2012 was presented. It was found a significant increase (P<0.05) in prevalence of anemia among females compared to males (1.42/1 ratio). The prevalence for Sickle cell anemia was (38.38%) which showed highly significant increase comparing with (P>0.01) 2-Thalassmia (5.32%) and Non A2 Hemoglobin (2.90%). 2-Thalassmia also, showed significant increase P<0.05) compared with Non A2 Hemoglobin. Hemoglobinopathies occurs frequently among our patients, with majority of cases having Sickle cells anaemia, and cases with heterozygous mutation (trait disease) was the predominant.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Fetal Hemoglobin on RBC Parameters among Sickle Cell Anemia Patients: A Cross Sectional Study from Makkah City; Western Saudi Arabia

Background: Sickle Cell Anemia (SCA) is the most common monogenic disorder that is inherited as an autosomal recessive pattern. Fetal hemoglobin (HbF) plays a major role in ameliorating clinical severity of the SCA where higher expression of HbF is associated with a reduction in the painful episode and thus reduces the number of hospitalization. The current work aimed to investigate the effect ...

متن کامل

Pulmonary Spirometry Parameters in Patients with Sickle Thalassemia and Sickle Cell Disease at Shafa Hospital in Khuzestan Province-Iran

Abstract Background Prevalence of hereditary blood diseases such as sickle cell anemia, sickle thalassemia and thalassemia major are high in Khuzestan province. Sickle cell anemia and beta-thalassemia are predominantly common in Iranian Arabs. Pulmonary complications account for a large proportion of morbidity and mortality in patients with and sickle cell disease. Periodic lung function asse...

متن کامل

Elucidation of βs/ Globin Gene clusters Haplotypes Related to Sickle Cell Anemia in Khuzestan Province, Southwest of Iran

Background & objectives: The researcher clarified that β/Globin gene cluster haplotypes in patients with sickle cell anemia provide useful population data as predictors of the disease severity, gene flow, and the origins of sickle cell mutation in this region. Materials and methods: A total of 150 subjects was investigated in two different groups for five polymorphism restriction site...

متن کامل

Prevalence of Intestinal Parasites among Patients of Al-Noor Specialist Hospital, Makkah, Saudi Arabia.

OBJECTIVES To determine the prevalence of intestinal parasites among patients of a tertiary care hospital. METHODS A total of 12,054 samples received from the outpatient as well as inpatient departments from January 1, 2004 to December 31, 2009 in Al-Noor Specialist Hospital, Makkah, Saudi Arabia. Stool examinations were performed by direct method and concentrated Techniques for all patients....

متن کامل

Genotyping of Individuals with Hemoglobinopathies in Beja Tribes and Other Minor Groups in Port Sudan, Eastern Sudan

ABSTRACT             Background and objectives: This study aimed to characterize the spectrum of β-thalassemia mutations and haplotypes of sickle cell anemia in Beja tribes and other minor groups living in Port Sudan, Sudan.             Methods: This descriptive cross-sectional study was carried out from March 2011 to July 2013. Overall, 209 anemic patients were screened for hemoglobinopathy ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013